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Finally, myosin inhibition takes centre stage

Introducing CAMZYOS® (mavacamten): The first and only licensed cardiac myosin inhibitor for symptomatic NYHA class II and III obstructive hypertrophic cardiomyopathy (HCM)1,2

CAMZYOS is a first-in-class non-invasive, selective, allosteric and reversible cardiac myosin inhibitor that targets the underlying pathophysiology of obstructive HCM.1,2 By reducing excess actin-myosin cross-bridge formation, CAMZYOS can help to normalise  contractility, reduce dynamic LVOT obstruction and improve cardiac filling pressures in patients with obstructive HCM.1,2

Explore CAMZYOS in the management of patients with symptomatic obstructive HCM


CAMZYOS (mavacamten) is indicated for the treatment of symptomatic (New York Heart Association, NYHA, class II-III) obstructive 
hypertrophic cardiomyopathy (oHCM) in adult patients.1

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HCM, hypertrophic cardiomyopathy; LVOT, left ventricular outflow tract; MoA, mechanism of action; NYHA, New York Heart Association.

References
  1. CAMZYOS (mavacamten) Summary of Product Characteristics. 
  2. Olivotto I et al. Lancet. 2020;396(10253):759–769.