Requirements for monitoring depend on LVEF and LVOT gradient. See Maintenance and interruption page for further information.

Introducing CAMZYOS® (mavacamten): The first and only licensed cardiac myosin inhibitor for symptomatic NYHA class II and III obstructive hypertrophic cardiomyopathy (HCM)1,2

CAMZYOS is a first-in-class non-invasive, selective, allosteric and reversible cardiac myosin inhibitor that targets the underlying pathophysiology of obstructive HCM.1,2 By reducing excess actin-myosin cross-bridge formation, CAMZYOS can help to normalise  contractility, reduce dynamic LVOT obstruction and improve cardiac filling pressures in patients with obstructive HCM.1,2

Explore CAMZYOS in the management of patients with symptomatic obstructive HCM

Want to learn more about CAMZYOS (mavacamten) for your eligible patients?


CAMZYOS (mavacamten) is indicated for the treatment of symptomatic (New York Heart Association, NYHA, class II-III) obstructive 
hypertrophic cardiomyopathy (oHCM) in adult patients.1

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*Echocardiogram assessment of Valsalva LVOT.1,2
Evaluation of symptoms via KCCQ-23 and HCMSQ-SoB.1,3,4

HCM, hypertrophic cardiomyopathy; HCMSQ-SoB, Hypertrophic Cardiomyopathy Symptom Questionnaire Shortness-of-Breath; KCCQ-23, Kansas City Cardiomyopathy Questionnaire-23; LVOT, left ventricular outflow tract; MoA, mechanism of action; NYHA, New York Heart Association.

References
  1. CAMZYOS (mavacamten) Summary of Product Characteristics. 
  2. Olivotto I et al. Lancet. 2020;396(10253):759–769.
  3. Spertus JA et al. Lancet. 2021;397(10293):2467–2475.
  4. Garcia-Pavia P et al. Eur Heart J. 2024;45(47):5071–5083.

3500-GB-2500119  |  October 2025